Total Body Irradiation

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Accepting patients

T Cell Receptor Depletion in Stem Cell Transplant

Alpha/Beta TCD HCT in Patients With Inherited BMF Disorders
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  • Monoclonal Antibody
  • T Cell (Allogeneic)
  • CD20
  • Phase 2

Accepting patients

A Phase I/II Clinical Trial of "Off-the-shelf" NK Cell Administration in Combination With Allogeneic SCT to Decrease Disease Relapse in Patients With High-risk Myeloid Malignancies Undergoing Matched Related, Matched Unrelated, One Antigen Mismatched Unrelated, or Haploidentical Stem-cell Transplantation
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  • Allogeneic Stem Cell Transplant
  • Natural Killer Cells (Allogeneic)
  • White Blood Cell Stimulant
  • Phase 1/2

Accepting patients

Treosulfan vs. Clofarabine-Based Conditioning

A Phase II Randomized Study to Assess Outcomes With Treosulfan-Based Versus Clofarabine-Based Conditioning in Patients With Myelodysplastic Syndromes (MDS), Chronic Myelomonocytic Leukemia (CMML), or Acute Myeloid Leukemia (AML) Undergoing Allogeneic Hematopoietic Cell Transplantation (HCT)
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  • Allogeneic Stem Cell Transplant
  • Antimetabolites
  • Phase 2

Accepting patients

Infusion of Expanded Cord Blood Cells

Pilot Study: Infusion of Off-the-Shelf Ex Vivo Expanded Cryopreserved Progenitor Cells (Dilanubicel) in the Setting of Single Cord Blood Transplantation for Patients With Hematologic Malignancies
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  • Cord Blood
  • Phase 2

Not currently accepting

211At-BC8-B10

A Phase I/II Study Evaluating Escalating Doses of 211At-Labeled Anti-CD45 MAb BC8-B10 (211At-BC8-B10) Followed by Related Haplo-Identical Allogeneic Hematopoietic Cell Transplantation for High-Risk Acute Leukemia or Myelodysplastic Syndrome (MDS)
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  • Allogeneic Stem Cell Transplant
  • Monoclonal Antibody
  • Phase 1/2

Accepting patients

CLAG-M or FLAG-Ida Chemotherapy

CLAG-M or FLAG-Ida Chemotherapy Followed Immediately by Related/Unrelated Reduced-Intensity Conditioning (RIC) Allogeneic Hematopoietic Cell Transplantation for Adults With Myeloid Malignancies at High Risk of Relapse: A Phase 1 Study
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  • Allogeneic Stem Cell Transplant
  • White Blood Cell Stimulant
  • Phase 1

Accepting patients

AB-CliniMACs

Unrelated And Partially Matched Related Donor Peripheral Stem Cell Transplantation With Alpha/Beta T Cell And B Cell Depletion For Patients With Hematologic Malignancies
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  • Allogeneic Stem Cell Transplant
  • T Cell
  • Phase 2

Accepting patients

Cytokine-Treated Veto Cells Post-Transplant

Cytokine-Treated Veto Cells in Treating Participants With Hematologic Malignancies Following Stem Cell Transplant
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  • Allogeneic Stem Cell Transplant
  • Phase 1/2

Accepting patients

Myeloablative Allo Stem Cell Transplant

Myeloablative Allogeneic Hematopoietic Stem Cell Transplant With Related or Unrelated Donor for Hematological Disorders
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  • Allogeneic Stem Cell Transplant
  • Phase 2

Accepting patients

UCB Transplant with Myeloablative Prep

Umbilical Cord Blood Transplantation Using a Myeloablative Preparative Regimen for Hematological Diseases
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  • Allogeneic Stem Cell Transplant
  • Phase 2