Cyclophosphamide
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ACCESS
HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide (ACCESS)
- Allogeneic Stem Cell Transplant
- Pre-Transplant
- Phase 2
Accepting patients
OPTIMIZE
A Phase II Study of Reduced Dose Post Transplantation Cyclophosphamide as GvHD Prophylaxis in Adult Patients With Hematologic Malignancies Receiving HLA-Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation
- Allogeneic Stem Cell Transplant
- Phase 2
Accepting patients
Optimized Cord Blood Transplant
Optimized Cord Blood Transplantation for the Treatment of High-Risk Hematologic Malignancies in Adults and Pediatrics
- Cord Blood
- Phase 2
Accepting patients
Donor Lymphocyte Infusion Post Transplant
Phase I/II Study Using Prophylactic Donor Lymphocyte Infusion Early Post-Transplant After Allogeneic Hematopoietic Cell Transplantation Using Post-Transplantation Cyclophosphamide for High-Risk Hematologic Malignancies
- Donor Lymphocyte Infusion (DLI)
- Post-Allogeneic Stem Cell Transplant
- Phase 1/2
Accepting patients
Total Marrow and Lymphoid Irradiation
Phase II Study of Evaluating the Efficacy of Total Marrow and Lymphoid Irradiation (TMLI) as the Conditioning Regimen for HLA-Haploidentical Hematopoietic Cell Transplantation in Patients With Myelodysplasia or Acute Leukemia
- Allogeneic Stem Cell Transplant
- Phase 2
Accepting patients
211At-BC8-B10
A Phase I/II Study Evaluating Escalating Doses of 211At-Labeled Anti-CD45 MAb BC8-B10 (211At-BC8-B10) Followed by Related Haplo-Identical Allogeneic Hematopoietic Cell Transplantation for High-Risk Acute Leukemia or Myelodysplastic Syndrome (MDS)
- Allogeneic Stem Cell Transplant
- Monoclonal Antibody
- Phase 1/2
Accepting patients
Infusion of Expanded Cord Blood Cells
Pilot Study: Infusion of Off-the-Shelf Ex Vivo Expanded Cryopreserved Progenitor Cells (Dilanubicel) in the Setting of Single Cord Blood Transplantation for Patients With Hematologic Malignancies
- Cord Blood
- Phase 2
Accepting patients
Graft Versus Host Disease-Reduction Strategies
A Phase II Randomized Controlled Trial Comparing GVHD-Reduction Strategies for Allogeneic Peripheral Blood Transplantation (PBSCT) for Patients With Acute Leukemia or Myelodysplastic Syndrome: Selective Depletion of CD45RA+ Naïve T Cells (TND) vs. Post-Transplantation Cyclophosphamide (PTCy)
- Allogeneic Stem Cell Transplant
- Phase 2
Accepting patients
T Cell Receptor Depletion in Stem Cell Transplant
Alpha/Beta TCD HCT in Patients With Inherited BMF Disorders
- Monoclonal Antibody
- T Cell (Allogeneic)
- CD20
- Phase 2
Accepting patients
Post-Transplant Cyclophosphamide
Haplo-identical Transplantation for Severe Aplastic Anemia, Hypo-plastic MDS and PNH Using Peripheral Blood Stem Cells and Post-transplant Cyclophosphamide for GVHD Prophylaxis
- Allogeneic Stem Cell Transplant
- Chemotherapy
- Phase 2