CPX-351

Vyxeos

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Accepting patients

CPX-351 (VYXEOS)

A Prospective, Single Site, Single-Arm Pilot Study of CPX-351 (VYXEOS) in Individuals < 22 Years With Secondary Myeloid Neoplasms
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  • Allogeneic Stem Cell Transplant
  • Chemotherapy
  • Steroid
  • Phase 2

Accepting patients

CPX-351 Plus Quizartinib

A Phase I/II Study of Liposomal Cytarabine and Daunorubicin (CPX-351) in Combination With Quizartinib in Patients With Acute Myeloid Leukemia (AML) and High Risk Myelodysplastic Syndrome (MDS)
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  • Tyrosine Kinase (TK) Inhibitor
  • Phase 1/2

Accepting patients

CPX-351

Phase 1 Dose Escalation Study of CPX-351 for Patients With Int-2 or High Risk IPSS Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia After Failure to Hypomethylating Agents
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  • Chemotherapy
  • Phase 1

Accepting patients

CPX-351 Plus Gemtuzumab Ozogamicin

A Pilot Study of Liposomal Cytarabine and Daunorubicin (CPX-351) in Combination With Gemtuzumab Ozogamicin (GO) in Relapsed Refractory Patients With Acute Myeloid Leukemia (AML) and Post-Hypomethylating Agent (Post-HMA) Failure High-Risk Myelodysplastic Syndrome (HR-MDS)
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  • Antibody Drug Conjugate (ADC)
  • Phase 2
  • Has results

Accepting patients

CPX-351 Plus Ivosidenib

Phase II Investigator Sponsored Study of CPX-351 in Combination With Ivosidenib for Patients With IDH1 Mutated Acute Myeloid Leukemia or High-Risk MDS
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  • IDH1 Inhibitor
  • Phase 2