Allogeneic Stem Cell Transplant

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Accepting patients

Bone Marrow & Kidney Transplant

Bone Marrow and Kidney Transplant for Patients With Chronic Kidney Disease and Blood Disorders (BMT)
  • Allogeneic Stem Cell Transplant
  • Phase 2

Accepting patients

Cord Blood Transplantation in Children

Cord Blood Transplantation in Children and Young Adults With Hematologic Malignancies and Non-malignant Disorders
  • Allogeneic Stem Cell Transplant
  • Phase 2

Accepting patients

Phase 1 Trial for Patients With Advanced Hematologic Malignancies Undergoing Reduced Intensity Allogeneic HCT With a T-cell Depleted Graft With Infusion of Conventional T-cells and Regulatory T-cells
  • Allogeneic Stem Cell Transplant
  • Phase 1

Not currently accepting

CD34+ Enriched Transplant

A Phase II Trial of CD34+ Enriched Transplants From HLA-Compatible Related or Unrelated Donors for Treatment of Patients With Myelodysplastic Syndrome
  • Allogeneic Stem Cell Transplant
  • CD34
  • Phase 2

Accepting patients

Treosulfan vs. Clofarabine-Based Conditioning

A Phase II Randomized Study to Assess Outcomes With Treosulfan-Based Versus Clofarabine-Based Conditioning in Patients With Myelodysplastic Syndromes (MDS), Chronic Myelomonocytic Leukemia (CMML), or Acute Myeloid Leukemia (AML) Undergoing Allogeneic Hematopoietic Cell Transplantation (HCT)
  • Allogeneic Stem Cell Transplant
  • Antimetabolites
  • Phase 2

Accepting patients

Total Marrow and Lymphoid Irradiation

Phase II Study of Evaluating the Efficacy of Total Marrow and Lymphoid Irradiation (TMLI) as the Conditioning Regimen for HLA-Haploidentical Hematopoietic Cell Transplantation in Patients With Myelodysplasia or Acute Leukemia
  • Allogeneic Stem Cell Transplant
  • Phase 2

Accepting patients

211At-BC8-B10

A Phase I/II Study Evaluating Escalating Doses of 211At-Labeled Anti-CD45 MAb BC8-B10 (211At-BC8-B10) Followed by Related Haplo-Identical Allogeneic Hematopoietic Cell Transplantation for High-Risk Acute Leukemia or Myelodysplastic Syndrome (MDS)
  • Allogeneic Stem Cell Transplant
  • Monoclonal Antibody
  • Phase 1/2

Accepting patients

Graft Versus Host Disease-Reduction Strategies

A Phase II Randomized Controlled Trial Comparing GVHD-Reduction Strategies for Allogeneic Peripheral Blood Transplantation (PBSCT) for Patients With Acute Leukemia or Myelodysplastic Syndrome: Selective Depletion of CD45RA+ Naïve T Cells (TND) vs. Post-Transplantation Cyclophosphamide (PTCy)
  • Allogeneic Stem Cell Transplant
  • Phase 2

Accepting patients

G-CSF Mobilized CD34+ Cells in Transplant

Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-Cells
  • Allogeneic Stem Cell Transplant
  • CD34
  • Phase 2

Accepting patients

Safety Study of Cord Blood Units

A Multicenter Safety Study of Unlicensed, Investigational Cryopreserved Cord Blood Units (CBUs) Manufactured by the National Cord Blood Program (NCBP) and Provided for Unrelated Hematopoietic Stem Cell Transplantation of Pediatric and Adult Patients
  • Allogeneic Stem Cell Transplant
  • Phase 2