Cord Blood Transplantation in Children

Cord Blood Transplantation in Children and Young Adults With Hematologic Malignancies and Non-malignant Disorders

What's the purpose of the trial?

This is a single-arm study to investigate 1-year treatment related mortality (TRM) in patients with life threatening non-malignant and malignant hematologic disorders who do not have a matched related donor for allogeneic transplantation.
Trial status

Accepting patients

Phase
Phase 2
Enrollment
31
Last Updated
3 weeks ago
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Participating Centers

There is one center participating in this trial. Enter a location below to view the distance.

Experimental Treatments

Learn more about the experimental treatments being evaluated in this clinical trial.

  • Allogeneic Stem Cell Transplant is a type of stem cell transplant that utilizes a donor's pre-collected stem cells to rescue the bone marrow from the toxic effects of very high dose chemotherapy.
  • Busulfan is a chemotherapy cancer medication that interferes with the growth and spread of cancer cells in the body, and may be used in the treatment of many different cancers.
  • Clofarabine is a chemotherapy medication that may be used in the treatment of many different cancers.
  • Cyclosporine is a drug that suppresses the immune system. It may be used in patients who have had organ transplants, autoimmune disorders, or graft vs host disease.
  • Fludarabine is a chemotherapy medication that may be used in the treatment of many different cancers.
  • Mycophenolate Mofetil is an immunosuppressive medication used to help prevent rejection in patients who have had a transplant.

Arms / Cohorts

Explore eligibility, treatments and learn more about potential cohorts.

Accepting patients

Participants with Non-Malignant and Malignant Hematologic Disorders

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