Thiotepa
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Accepting patients
Optimized Cord Blood Transplant
Optimized Cord Blood Transplantation for the Treatment of High-Risk Hematologic Malignancies in Adults and Pediatrics
- Cord Blood
- Phase 2
Accepting patients
Phase 1 Trial for Patients With Advanced Hematologic Malignancies Undergoing Reduced Intensity Allogeneic HCT With a T-cell Depleted Graft With Infusion of Conventional T-cells and Regulatory T-cells
- Allogeneic Stem Cell Transplant
- Phase 1
Accepting patients
Infusion of Expanded Cord Blood Cells
Pilot Study: Infusion of Off-the-Shelf Ex Vivo Expanded Cryopreserved Progenitor Cells (Dilanubicel) in the Setting of Single Cord Blood Transplantation for Patients With Hematologic Malignancies
- Cord Blood
- Phase 2
Accepting patients
Graft Versus Host Disease-Reduction Strategies
A Phase II Randomized Controlled Trial Comparing GVHD-Reduction Strategies for Allogeneic Peripheral Blood Transplantation (PBSCT) for Patients With Acute Leukemia or Myelodysplastic Syndrome: Selective Depletion of CD45RA+ Naïve T Cells (TND) vs. Post-Transplantation Cyclophosphamide (PTCy)
- Allogeneic Stem Cell Transplant
- Phase 2
Accepting patients
Venetoclax as Part of Pre-Transplant Chemotherapy
Venetoclax to Improve Outcomes of Fractionated Busulfan Regimen in Patients With High-Risk AML and MDS
- BCL-2 Inhibitor
- Phase 2
Accepting patients
IS-free Treg Stem Cell Transplant
A Pilot/Phase 1 Study of Immunosuppression-free Regulatory T-cell Graft-engineered Haploidentical Hematopoietic Cell Transplantation in Relapsed/Refractory AML/MDS
- Allogeneic Stem Cell Transplant
- Phase 1
Accepting patients
Naïve T Cell Depletion
Multi-Center Phase II Randomized Controlled Trial of Naïve T Cell Depletion for Prevention of Chronic Graft-Versus-Host Disease in Children and Young Adults
- Allogeneic Stem Cell Transplant
- Phase 2
Accepting patients
Orca-T
A Single Center, Non-Randomized, Phase 1b Study of Orca-T Following Escalated Dose of Total Marrow and Lymphoid Irradiation in Patients With Acute Leukemias and MDS
- T Cell (Allogeneic)
- Phase 1
Not yet accepting
Abatacept in Double Cord Blood Unit Transplant
ABBA CORD: Double Umbilical Cord Blood Transplants With Abatacept for Graft Versus Host Disease Prophylaxis
- Immunomodulatory Drug
- T Cell
- Phase 2
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