Ivosidenib

Tibsovo

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Accepting patients

CPX-351 Plus Ivosidenib

Phase II Investigator Sponsored Study of CPX-351 in Combination With Ivosidenib for Patients With IDH1 Mutated Acute Myeloid Leukemia or High-Risk MDS
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  • IDH1 Inhibitor
  • Phase 2

Accepting patients

Ivosidenib (AG120)

Phase Ib/II Investigator Initiated Study of the IDH1-Mutant Inhibitor Ivosidenib (AG120) With the BCL2 Inhibitor Venetoclax +/- Azacitidine in IDH1-Mutated Hematologic Malignancies
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  • BCL-2 Inhibitor
  • Hypomethylating Agents (HMA)
  • IDH1 Inhibitor
  • Phase 1/2
  • Has results

Accepting patients

Ivosidenib and Combination Chemotherapy

Phase 1 Trial of Ivosidenib and FLAG Chemotherapy in Relapsed/Refractory IDH1+ Acute Myeloid Leukemia (AML)
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  • IDH1 Inhibitor
  • MIDH2 Inhibitor
  • White Blood Cell Stimulant
  • Phase 1

Accepting patients

AG-120

A Phase I, Multicenter, Open-Label, Dose-Escalation and Expansion, Safety, Pharmacokinetic, Pharmacodynamic, and Clinical Activity Study of Orally Administered AG-120 in Subjects With Advanced Hematologic Malignancies With an IDH1 Mutation
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  • IDH1 Inhibitor
  • Phase 1