Idarubicin
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Accepting patients
A Combination of Cladribine, Idarubicin, Cytarabine (CLIA) and Quizartinib for the Treatment of Patients With Newly Diagnosed or Relapsed/Refractory Acute Myeloid Leukemia (AML) and High-Risk Myelodysplastic Syndrome (MDS))
Learn more- Tyrosine Kinase (TK) Inhibitor
- Phase 1/2
Accepting patients
Chemotherapy Plus Venetoclax
Phase II Study of Cladribine Plus Idarubicin Plus Cytarabine (ARAC) in Patients With AML, HR MDS, or Myeloid Blast Phase of CML
Learn more- BCL-2 Inhibitor
- Kinase Inhibitor
- Tyrosine Kinase (TK) Inhibitor
- Phase 2
Accepting patients
Gemtuzumab as Part of Chemotherapy
A Phase 2 Study of Fludarabine, Cytarabine, Filgrastim-sndz,Gemtuzumab Ozogamicin and Idarubicin in Newly Diagnosed Core Binding Factor Associated Acute Myelogenous Leukemia
Learn more- Antibody Drug Conjugate (ADC)
- Hypomethylating Agents (HMA)
- White Blood Cell Stimulant
- CD33
- Phase 2
Accepting patients
Heart Protection w/Dexrazoxane During Chemotherapy
Cardioprotection With Dexrazoxane in Acute Myeloid Leukemia (AML), High-Risk Myelodysplastic Syndrome (MDS), Myeloid Blast Phase of Chronic Myeloid Leukemia (CML), Ph+ AML, and Myeloid Blast Phase of Myeloproliferative Neoplasms
Learn more- Chemotherapy
- Phase 2
Accepting patients
Venetoclax w/ Combination Chemotherapy
A Phase 1b/2 Study of the BCL-2 Inhibitor Venetoclax in Combination With Standard Intensive AML Induction/Consolidation Therapy With FLAG-IDA in Patients With Newly Diagnosed or Relapsed/Refractory AML
Learn more- BCL-2 Inhibitor
- Chemotherapy
- Phase 1/2
Accepting patients
Identification of Drug Sensitization
Identification of AML/MDS Drug Sensitization by in Vivo Chemotherapy Administration
Learn moreAccepting patients
CLAG-M or FLAG-Ida Chemotherapy
CLAG-M or FLAG-Ida Chemotherapy Followed Immediately by Related/Unrelated Reduced-Intensity Conditioning (RIC) Allogeneic Hematopoietic Cell Transplantation for Adults With Myeloid Malignancies at High Risk of Relapse: A Phase 1 Study
Learn more- Allogeneic Stem Cell Transplant
- White Blood Cell Stimulant
- Phase 1
Accepting patients
PVEK (IMGN632)
Phase 1 Study of FLAG-Ida With Pivekimab Sunirine (PVEK [IMGN632]) for Adults With Newly Diagnosed Adverse-Risk Acute Myeloid Leukemia and Other High-Grade Myeloid Neoplasms
Learn more- Antibody Drug Conjugate (ADC)
- CD123
- Phase 1
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