University of Alabama at Birmingham

O'Neal Comprehensive Cancer Center

Birmingham, AL

Accepting patients

NTX-301

A Phase 1 Study of NTX-301, an Oral DNMT1 Inhibitor, in Patients With MDS and AML
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  • DNMT1 Inhibitor
  • Phase 1

Accepting patients

LIMBER

A Phase 1, Open-Label, Safety and Tolerability Study of INCB057643 in Participants With Myelofibrosis and Other Advanced Myeloid Neoplasms
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  • BET Inhibitor
  • JAK1 Inhibitor
  • JAK2 Inhibitor
  • Phase 1

Accepting patients

VIP943

An Open-label, Multicenter Phase 1 Study to Characterize Safety, Tolerability, Preliminary Antitumor Activity, Pharmacokinetics, and Pharmacodynamics of VIP943 Monotherapy in Subjects With Advanced CD123+ Hematologic Malignancies
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  • Antibody Drug Conjugate (ADC)
  • Kinesin Spindle Protein (KSP) Inhibitor
  • CD123
  • Phase 1

Not yet accepting

2 Step ATG

Phase II Clinical Trial of 2 Step ATG Combined With Tacrolimus and Mini Methotrexate for Prevention of Acute GVHD Post Myeloablative Allogeneic Stem Cell Transplant
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  • Phase 2

Not yet accepting

GVHD Prevention Using CliniMACS

Feasibility Study of CD34 Selection for GVHD Prophylaxis Using the Automated CliniMACS
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  • CD34
  • Phase 1

Not yet accepting

ATG Dosing for GVHD Prevention

Phase II Clinical Trial of 2 Step ATG Combined With Tacrolimus and Mini Methotrexate for Prevention of Acute GVHD Post Reduced Intensity Allogeneic Stem Cell Transplant
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  • Phase 2