DISC-0974

A Phase 1b/2a Open-label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DISC-0974 in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia

What's the purpose of the trial?

This phase 1b/2a open-label study will assess the safety, tolerability, pharmacokinetics and pharmacodynamics of DISC-0974 as well as categorize the effects on anemia response in subjects with myelofibrosis or myelodysplastic syndrome and anemia.
Trial status

Accepting patients

Phase
Phase 1/2
Enrollment
56
Last Updated
4 days ago
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Participating Centers

There are 12 centers participating in this trial. Enter a location below to find the closest center.

Experimental Treatments

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  • DISC-0974 is a monoclonal antibody that may help to increase iron levels in patients with certain blood disorders and cancers.

Arms / Cohorts

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Accepting patients

Dose Escalation

Accepting patients

Dose Expansion

Accepting patients

Exploratory MDS Cohort

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