HMPL-306

A Phase 1, Open-Label, Multicenter Study of HMPL-306 in Advanced Hematological Malignancies With Isocitrate Dehydrogenase (IDH) Mutations

What's the purpose of the trial?

An open label single-arm clinical trial to evaluate the safety, tolerability, PK, PD, and preliminary efficacy of HMPL-306 in subjects with advanced relapsed, refractory, or resistant hematological malignancies that harbor IDH mutations.
Trial status

Accepting patients

Phase
Phase 1
Enrollment
75
Last Updated
3 weeks ago
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Participating Centers

There are 7 centers participating in this trial. Enter a location below to find the closest center.

Experimental Treatments

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  • HMPL-306 is an oral small molecule IDH1 and IDH2 inhibitor. It's being studied for use in several different cancers.

Arms / Cohorts

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Accepting patients

Treatment

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