Graft Versus Host Disease-Reduction Strategies

A Phase II Randomized Controlled Trial Comparing GVHD-Reduction Strategies for Allogeneic Peripheral Blood Transplantation (PBSCT) for Patients With Acute Leukemia or Myelodysplastic Syndrome: Selective Depletion of CD45RA+ Naïve T Cells (TND) vs. Post-Transplantation Cyclophosphamide (PTCy)

Arms / Cohorts

Experimental, Arm A1:Total Body Irradiation Based

Accepting patients

Experimental, Arm A2:Busulfan Based

Accepting patients

Experimental, Arm C1:TBI, PTCy, tacrolimus)

Accepting patients

Experimental, Arm C2:Busulfan, PTCy, tacrolimus)

Accepting patients

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