A Phase 2, Single Arm Study of Luspatercept for the Treatment of Anemia in Lower Risk Myelodysplastic Syndromes (MDS) or Non-Proliferative Myelodysplastic Syndromes/ Myeloproliferative Neoplasms (MDS/MPN)

What's the purpose of the trial?

The purpose of the study is to see if participants with anemia due to their type of MDS or MDS/MPN will experience a more decreased need for regular blood transfusions if they take luspatercept plus best supportive care, and what effect, good and/or bad, luspatercept has on them and their anemia due to MDS or MDS/MPN. The safety and tolerability of luspatercept will also be evaluated in this study.
Trial status

Accepting patients

Phase
Phase 2
Enrollment
70
Last Updated
4 weeks ago
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Experimental Treatments

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  • Luspatercept is an agent that helps your bone marrow finish making red blood cells that have started to form.

Arms / Cohorts

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Accepting patients

Gene Mutations Other Than SF3B1

Accepting patients

SF3B1 Gene Mutation

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