ASTX727

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Accepting patients

MyeloMATCH Master Protocol

Master Screening and Reassessment Protocol (MSRP) for the NCI MyeloMATCH Clinical Trials
  • Genetic Sequencing
  • Phase 2

Not yet accepting

ASTX727 in Patients with Hepatic Impairment

A Phase 1b, Open-label, Parallel Group, Multiple-dose Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Oral Decitabine and Cedazuridine (ASTX727) in Cancer Patients With Moderate and Severe Hepatic Impairment
  • Chemotherapy
  • Hypomethylating Agents (HMA)
  • Phase 1

Accepting patients

Decitabine and Cedazuridine (ASTX727)

A Phase 1b, Open-label, Parallel Group, Multiple-dose Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Oral Decitabine and Cedazuridine (ASTX727) in Cancer Patients With Severe Renal Impairment and Cancer Patients With Normal Renal Function
  • Cytidine Deaminase Inhibitor
  • DNMT1 Inhibitor
  • Hypomethylating Agents (HMA)
  • Phase 1