University of Minnesota - Masonic Cancer Center
Minneapolis, MN
Accepting patients
Reduced Intensity Conditioning Treosulfan
MT2025-35 Allogeneic Hematopoietic Stem Cell Transplantation Using Reduced Intensity Conditioning Treosulfan and Fludarabine, With Post-Transplant Cytoxan (PTCy) for the Treatment of Hematological Diseases
- Allogeneic Stem Cell Transplant
- Phase 2
Accepting patients
Imetelstat Combination Therapy
A Phase 1 Study of GRN163L (Imetelstat) in Combination With Fludarabine and Cytarabine for Patients With Acute Myeloid Leukemia That is in Second or Greater Relapse or That is Refractory to Relapse Therapy; Myelodysplastic Syndrome or Juvenile Myelomonocytic Leukemia in First or Greater Relapse or is Refractory to Relapse Therapy
- Telomerase Inhibitor
- Phase 1
Accepting patients
GTB-3650 Tri-Specific Killer Engager (TriKE®)
HM2023-05: GTB-3650 (Anti-CD16/IL-15/Anti-CD33) Tri-Specific Killer Engager (TriKE®) for the Treatment of High Risk Myelodysplastic Syndromes (MDS) and Refractory/Relapsed Acute Myeloid Leukemia (AML)
- Interleukin 15 (IL-15)
- CD33
- CD16
- Phase 1
Accepting patients
TRX-103
Phase I, First in Human, Open Label Study to Evaluate Safety and Tolerability of TRX103 Cells in Subjects With Hematological Malignancies Undergoing HLA-mismatched Related or Unrelated Hematopoietic Stem Cell Transplantation (HSCT)
- T Cell (Allogeneic)
- Post-Allogeneic Stem Cell Transplant
- Phase 1
Accepting patients
PedAL Screening
Pediatric Acute Leukemia (PedAL) Screening Trial - Developing New Therapies for Relapsed Leukemias
- Phase 1/2
Accepting patients
T Cell Receptor Depletion in Stem Cell Transplant
Alpha/Beta TCD HCT in Patients With Inherited BMF Disorders
- T Cell (Allogeneic)
- Monoclonal Antibody
- CD20
- Phase 2
Accepting patients
A/B TCD Peripheral Blood Stem Cell Transplantation
Phase II, Open-Label, Prospective Study of T Cell Receptor Alpha/Beta Depletion (A/B TCD) Peripheral Blood Stem Cell (PBSC) Transplantation for Children and Adults With Hematological Malignancies
- Allogeneic Stem Cell Transplant
- Phase 2
Accepting patients
Allogeneic Stem Cell Transplant
MT2023-20: Hematopoietic Cell Transplant With Reduced Intensity Conditioning and Post-transplant Cyclophosphamide for Severe Aplastic Anemia and Other Forms of Acquired Bone Marrow Failure.
- Allogeneic Stem Cell Transplant
- Phase 2
Accepting patients
Post-Transplant Cytoxan
Allogeneic Hematopoietic Stem Cell Transplantation Using Reduced Intensity Conditioning (RIC) With Post-Transplant Cytoxan (PTCy) for the Treatment of Hematological Diseases
- Allogeneic Stem Cell Transplant
- Xanthine Oxidase Inhibitor
- Phase 2
Accepting patients
Myeloablative Allo Stem Cell Transplant
Myeloablative Allogeneic Hematopoietic Stem Cell Transplant With Related or Unrelated Donor for Hematological Disorders
- Allogeneic Stem Cell Transplant
- Phase 2