Sylvester Comprehensive Cancer Center (Main)
University of Miami Health System
Miami, FL
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Accepting patients
ACCESS
HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide (ACCESS)
Learn more- Allogeneic Stem Cell Transplant
- Pre-Transplant
- Phase 2
Accepting patients
R289
Phase 1b Study of R289 in Patients with Lower-risk Myelodysplastic Syndromes (LR MDS)
Learn more- IRAK 1 Inhibitor
- IRAK 4 Inhibitor
- Phase 1/2
Accepting patients
SX-682
A Phase 1, Open-Label, Dose-Escalation With Expansion Study of SX-682 Alone and in Combination With Oral or Intravenous Decitabine in Subjects With Myelodysplastic Syndrome
Learn more- CXCR1 Inhibitor
- CXCR2 Inhibitor
- Phase 1
- Has results
Accepting patients
NC525
A Phase 1, Open-Label, Safety, Tolerability, And Efficacy Study of NC525 in Subjects With Advanced Myeloid Neoplasms
Learn more- Monoclonal Antibody
- Phase 1
Accepting patients
NEROFE
An Open-Label Phase 1b Study of NEROFE, a Novel Hormone-Peptide in Adult Patients With Advanced Myelodysplastic Syndrome (MDS) and Acute Myelogenous Leukemia (AML)
Learn more- Phase 1
Accepting patients
Luspatercept and Lenalidomide (L2)
A Multicenter, Phase Ib/II Study That Combines Luspatercept and Lenalidomide (L2) in Lower-risk, Non-del(5q) MDS Patients
Learn more- Erythroid Maturation Agent (EMA)
- Immunomodulatory Drug
- Red Blood Cell Stimulant
- Phase 1/2
Accepting patients
Mismatched Related vs. Matched Unrelated Donor
A Multi-Center, Phase 3, Randomized Trial of Matched Unrelated Donor (MUD) Versus HLA-Haploidentical Related (Haplo) Myeloablative Hematopoietic Cell Transplantation for Children, Adolescents, and Young Adults (AYA) With Acute Leukemia or Myelodysplastic Syndrome (MDS)
Learn more- Allogeneic Stem Cell Transplant
- Monoclonal Antibody
- Phase 3
Accepting patients
KER-050
A Phase 2, Open-Label, Ascending Dose Study of KER-050 for the Treatment of Anemia in Patients With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS)
Learn more- Growth Factor
- Phase 2
- Has results
Accepting patients
LIMBER
A Phase 1, Open-Label, Safety and Tolerability Study of INCB057643 in Participants With Myelofibrosis and Other Advanced Myeloid Neoplasms
Learn more- BET Inhibitor
- JAK1 Inhibitor
- JAK2 Inhibitor
- Phase 1
Accepting patients
OPTIMIZE
A Phase II Study of Reduced Dose Post Transplantation Cyclophosphamide as GvHD Prophylaxis in Adult Patients With Hematologic Malignancies Receiving HLA-Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation
Learn more- Allogeneic Stem Cell Transplant
- Phase 2