Barbara Ann Karmanos Cancer Institute
Wayne State University
Detroit, MI
Accepting patients
OPTIMIZE
A Phase II Study of Reduced Dose Post Transplantation Cyclophosphamide as GvHD Prophylaxis in Adult Patients With Hematologic Malignancies Receiving HLA-Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation
- Allogeneic Stem Cell Transplant
- Phase 2
Accepting patients
BMT CTN 2203
A Randomized, Multicenter, Phase III Trial of Tacrolimus/Methotrexate/Ruxolitinib Versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation
- JAK1 Inhibitor
- JAK2 Inhibitor
- Tyrosine Kinase (TK) Inhibitor
- Post-Allogeneic Stem Cell Transplant
- Randomization
- Phase 3
Accepting patients
LYT-200
A Phase 1 Open-label, Multi-center Study of the Safety, Pharmacokinetics (PK), and Anti-tumor Activity of LYT- 200 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML), or With Relapsed/Refractory, High-risk Myelodysplastic Syndrome (MDS)
- Monoclonal Antibody
- Galectin-9 Protein
- Phase 1
- Has results
Accepting patients
[F-18] FLT for Imaging
Use of [F-18] FLT for Imaging With Positron Emission Tomography (PET)
- Observational Trial
Accepting patients
TCR Engineered Donor T-Cells
A Study of TSC-100 and TSC-101 in AML, ALL and MDS in Patients Undergoing Allogeneic Peripheral Blood Stem Transplantation
- T Cell (Allogeneic)
- Phase 1
- Has results
Accepting patients
MyeloMATCH Master Protocol
Master Screening and Reassessment Protocol (MSRP) for the NCI MyeloMATCH Clinical Trials
- Genetic Sequencing
- Phase 2
Not currently accepting
Cord Blood Units for Neutrophil Recovery
A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs) for Transplantation in Pediatric and Adult Patients With Hematologic Malignancies and Other Indications
- Cord Blood
- Observational Trial
- Monoclonal Antibody
- Phase 1